A Legacy of Innovation in Aesthetic Medicine
Plinest® is the flagship aesthetic medicine line by Mastelli, a family-owned Italian biopharmaceutical company with more than 70 years of expertise in regenerative medicine. Rooted in Sanremo since 1952 and backed by over 100 scientific publications, Mastelli has pioneered the use of Polynucleotides High Purification Technology (PN HPT™) – a powerful, natural-origin DNA extract derived from freshwater salmon trout.
This unique technology enhances fibroblast activity, promotes tissue repair, and regenerates the skin from within. Plinest® is a medical device based on PN HPT™, created to improve skin quality, elasticity, and radiance through an evidence-based and holistic approach.
Priming: Preparing Skin for Regeneration
Plinest® introduces a new vision in aesthetic treatments through the concept of Priming – preparing the skin to enhance and prolong the effects of procedures like lasers, peels, fillers, radiofrequency, and surgery. The result? Visibly rejuvenated skin with improved tone, firmness, and smoothness.
A Full-Body Regeneration Line
Whether it’s facial rejuvenation, delicate eye contour care, or addressing thinning hair, Plinest® delivers targeted solutions tailored to modern aesthetic needs.
Plinest Range
Dermacircle – Authorised Mastelli Aesthetics® Distributor in Greece & Cyprus.