RADIESSE® is the only evidence-based regenerative biostimulator[1] that stimulates new collagen and elastin with the versatility to also provide immediate volume and sharpened contours – for up to 12 months or longer in most patients.[1-6]
RADIESSE® is also the only evidence-based regenerative biostimulator[1] that reverses visible signs of aging and creates a more natural, youthful appearance. [2,7]
• Improves skin foundation[8,9]
• Meaningfully rebuilds skin[10]
• Renews healthy-looking skin* tissue[1,11]
• Provides immediate lift and sharpened contours[3]
• Effectively regenerates skin over the long-term[3,4]
It can be used in a variety of indications and injection sites, offering versatility and flexibility to provide a wide range of personalized treatments.[5,6]
How does RADIESSE® work?
- RADIESSE® is a unique, evidence-based treatment[1] that works to regenerate and restore the natural components of your skin to provide structure and support for more youthful looking, firmer skin.[1,7,8]
- Acts directly to stimulate the creation of collagen, and key components of the skin’s structure to work against the signs of aging skin. [8,9]
- Stimulates production of collagen and elastin, to provide support and structure to the skin and help smooth out wrinkles. [8,10]
- Can reverse the visible signs of aging, providing long-term skin regeneration for up to 12 months or more. [1,6,11]
Benefits of using RADIESSE®
- Up to 73.5% of patients saw improvements in décolleté wrinkles and lines lasting 16 weeks after treatment*. [12]
- 76.1% of patients saw enhancements in skin quality lasting 16 weeks after treatment. †[12]
- Doctors were satisfied with the décolleté treatment of 77% of patients at 16 weeks after treatment. [12]
RADIESSE® is made up of particles called microspheres which are specifically designed to stimulate not only new collagen growth but also key components of the skin, helping to reverse the visible signs of aging [1,7,8].
Dermacircle – Authorised Merz Aesthetics® Distributor in Greece & Cyprus of RADIESSE®, BELOTERO® and ULTHERAPY® which are pending trademarks and/or registered trademarks of the Merz Group companies in the EU and/or other countries.
Citations
*Improved at-rest appearance defined as a ≥1-point improvement on the Merz Aesthetics Scales Décolleté Wrinkles-At Rest assessed by the blinded live rater, analysed using a modified full analysis set with missing data replaced by a multiple imputation approach. 73.5% of patients showed improvement in appearance of at-rest décolleté wrinkles following two treatments. In the primary endpoint of the study,73.5% of patients pooled across treatment groups showed an improvement in the at-rest appearance of décolleté wrinkles 16 weeks after their last treatment.[12]
† Level of improvement in skin quality assessed according to iGAIS – Investigator Global Aesthetics Improvement Scale.[12]
1.Kim, J. Clin Cosmet Investig Dermatol. 2019;12:771–784
2.Yutskovskaya, Y, et al. J Drugs Dermatol. 2014;13(9):1047–1052
3.Durkin, A, et al. J Cosmet Dermatol. 2021;20(2):442–450
4.Baspeyras, M, et al. J Cosmet Dermatol. 2017;16(3):342–347
5.Pavicic, T. J Drugs Dermatol. 2013;12(9):996–1002.
6.RADIESSE®. Instructions for use. 2023.
7. Yutskovskaya, YA, et al. J Drugs Dermatol. 2020;19(4):405–411.
8. González, N, Goldberg, DJ. Dermatol Surg. 2019;45(4):547–551.
9. Wollina, U, Goldman, A. Dermatol Ther. 2020;33(6):e14183.
10. Courderot-Masuyer, C, et al. J Cosmet Dermatol. 2016;15(3):260–268.
11. Fabi, SG, et al. J Drugs Dermatol. 2021;20(5):534–537.
12. Merz Aesthetics®. Data on File. 2023.
13. Yutskovskaya, YA, Kogan,EA. J Drugs Dermatol. 2017;16(1):68–74.
14. Fisher, GJ, et al. Arch Dermatol. 2008;144(5):666–672.
15. Bass, LS, et al. Aesthet Surg J. 2010;30(2):235–238.
16.Van Loghem, J, et al. J Clin Aesthet Dermatol. 2015;8(1):38–49.
17. Draoui, O. The story of calcium hydroxylapatite. In: van Loghem, J, ed.Calcium Hydroxylapatite Soft Tissue Fillers. 2021.